I’m not aware of anyone with the new Maslow 4 having posted about cutting acrylic, but I know some posts have been made by users with the older Maslow design, which moves slower, so it may not cut as cleanly. Your request (cutting acrylic for a neon design) seems rather specific. Were you looking for some feature specific to neon, like through holes for the tubing, or do you just want to see how the Maslow does on acrylic? Also, polycarbonate is generally easier to work with than acrylic. It’s less brittle, so it is less likely to crack.
This topic shows a project in acrylic with the original Maslow. It’s not for neon, but it does discuss how to cut acrylic with a Maslow.