Timeout communicating with programmer

Can anyone help me with this? Cant upload firmware…

Arduino:1.8.14 Hourly Build 2021/01/29 11:33 (Windows 10), Kort"Arduino Mega or Mega 2560, ATmega2560 (Mega 2560)"

Skissen bruker 57294 bytes (22%) av program lagrings minnet. Maks er 253952 bytes

avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: stk500v2_getsync(): timeout communicating with programmer

Welcome!

That seems like it could be an issue with the wrong COM port. Do you feel confident that you have the right one?